South Orange County, CA www.linkedin.com/in/angieknierim

Some leaders have a vision but no one to break it down, build the structure, and own the execution. I close that gap.
I partner with senior leaders and executive teams to build the operational infrastructure that makes strategy real: governance systems, cross-functional alignment, portfolio clarity, and the kind of complete ownership that lets leaders focus on what only they can do.
My background is rooted in engineering, operations and IT, built across medical device and life sciences environments spanning Fortune 500 corporations and mission-driven organizations. I bring the technical fluency to operate alongside engineers, scientists, regulatory, and technology teams, and the strategic range to work at the executive level. I’m equally comfortable in the boardroom and in the weeds, and I know when each one is needed.
Whether the role is Chief of Staff, Business Transformation Leader, or Principal Program Manager, I'm the person teams don't know they're missing until I'm there.
Led governance, process improvement, and organizational development initiatives across two contracts. Built the Technical Communications Governance Board from the ground up, rationalizing a 168-project portfolio into 14 high-impact initiatives, then built the executive cadence and led the departmental restructuring, for a 70-member team, that sustained it going forward. Built risk infrastructure through a CAPA investigation, including a RAID log and Root Cause Analysis (RCA) training program, and a fiscal-year goal development and adherence system that replaced ad hoc goal-setting with a lasting, data-driven process. Also led the requirements-driven literature program and the Customer-Centered Design Initiative.
Led compliance, data management, and labeling programs across three contracts spanning Global Labeling & IT, Global Supply Chain and Finance. Partnered with the VP of Finance and Director of Global Supply Chain to build a Master Data Management program from the ground up across 7 sites, surfacing 60 pain points and scoping 4 follow-on projects. Led a separate Product Data Assessment Initiative across five business units to define the organization's product data landscape. Program Manager for Global Supply Chain on the EU MDR UDI initiative, defining scope, schedule, risk, and KPIs across Regulatory, IT, and business teams. Under the Global Labeling function, led a five-vendor RFP and process redesign for a new eLabeling program, targeting 30%+ reduction in distribution center kitting and $200K per year in discard savings.
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